Bacteria activate sensory neurons that modulate pain and inflammation.

Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck Wardenburg J, Hwang SW, Carroll MC, Woolf CJ
Nature (2013) | 944 citations

Follicular dendritic cells: dynamic antigen libraries.

Heesters BA, Myers RC, Carroll MC
Nature reviews. Immunology (2014) | 529 citations

Endocytosis and recycling of immune complexes by follicular dendritic cells enhances B cell antigen binding and activation.

Heesters BA, Chatterjee P, Kim YA, Gonzalez SF, Kuligowski MP, Kirchhausen T, Carroll MC
Immunity (2013) | 327 citations

Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response.

Golebski K, Layhadi JA, Sahiner U, Steveling-Klein EH, Lenormand MM, Li RCY, Bal SM, Heesters BA, Vilà-Nadal G, Hunewald O, Montamat G, He FQ, Ollert M, Fedina O, Lao-Araya M, Vijverberg SJH, Maitland-van der Zee AH, van Drunen CM, Fokkens WJ, Durham SR, Spits H, Shamji MH
Immunity (2021) | 228 citations

Trafficking of B cell antigen in lymph nodes.

Gonzalez SF, Degn SE, Pitcher LA, Woodruff MC, Heesters BA, Carroll MC
Annual review of immunology (2011) | 222 citations

Antigen Presentation to B Cells.

Heesters BA, van der Poel CE, Das A, Carroll MC
Trends in immunology (2016) | 206 citations

IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation.

Golebski K, Ros XR, Nagasawa M, van Tol S, Heesters BA, Aglmous H, Kradolfer CMA, Shikhagaie MM, Seys S, Hellings PW, van Drunen CM, Fokkens WJ, Spits H, Bal SM
Nature communications (2019) | 137 citations

KLRG1 and NKp46 discriminate subpopulations of human CD117(+)CRTH2(-) ILCs biased toward ILC2 or ILC3.

Nagasawa M, Heesters BA, Kradolfer CMA, Krabbendam L, Martinez-Gonzalez I, de Bruijn MJW, Golebski K, Hendriks RW, Stadhouders R, Spits H, Bal SM
The Journal of experimental medicine (2019) | 129 citations

Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes.

Heesters BA^*, Lindqvist M, Vagefi PA, Scully EP, Schildberg FA, Altfeld M, Walker BD, Kaufmann DE, Carroll MC
PLoS pathogens (2015) | 116 citations

Follicular Dendritic Cell Activation by TLR Ligands Promotes Autoreactive B Cell Responses.

Das A, Heesters BA, Bialas A, O'Flynn J, Rifkin IR, Ochando J, Mittereder N, Carlesso G, Herbst R, Carroll MC
Immunity (2017) | 104 citations

Steroid-resistant human inflammatory ILC2s are marked by CD45RO and elevated in type 2 respiratory diseases.

van der Ploeg EK, Golebski K, van Nimwegen M, Fergusson JR, Heesters BA, Martinez-Gonzalez I, Kradolfer CMA, van Tol S, Scicluna BP, de Bruijn MJW, de Boer GM, Tramper-Stranders GA, Braunstahl GJ, van IJcken WFJ, Nagtegaal AP, van Drunen CM, Fokkens WJ, Huylebroeck D, Spits H, Hendriks RW, Stadhouders R, Bal SM
Science immunology (2021) | 97 citations

Trans-nodal migration of resident dendritic cells into medullary interfollicular regions initiates immunity to influenza vaccine.

Woodruff MC, Heesters BA, Herndon CN, Groom JR, Thomas PG, Luster AD, Turley SJ, Carroll MC
The Journal of experimental medicine (2014) | 91 citations

Complexity and Diversity of the Mammalian Sialome Revealed by Nidovirus Virolectins.

Langereis MA, Bakkers MJ, Deng L, Padler-Karavani V, Vervoort SJ, Hulswit RJ, van Vliet AL, Gerwig GJ, de Poot SA, Boot W, van Ederen AM, Heesters BA, van der Loos CM, van Kuppeveld FJ, Yu H, Huizinga EG, Chen X, Varki A, Kamerling JP, de Groot RJ
Cell reports (2015) | 77 citations

The murine coronavirus hemagglutinin-esterase receptor-binding site: a major shift in ligand specificity through modest changes in architecture.

Langereis MA, Zeng Q, Heesters BA, Huizinga EG, de Groot RJ
PLoS pathogens (2012) | 63 citations

Loss of intestinal sympathetic innervation elicits an innate immune driven colitis.

Willemze RA, Welting O, van Hamersveld P, Verseijden C, Nijhuis LE, Hilbers FW, Meijer SL, Heesters BA, Folgering JHA, Darwinkel H, Blancou P, Vervoordeldonk MJ, Seppen J, Heinsbroek SEM, de Jonge WJ
Molecular medicine (Cambridge, Mass.) (2019) | 59 citations

How the COVID-19 pandemic highlights the necessity of animal research.

Genzel L, Adan R, Berns A, van den Beucken JJJP, Blokland A, Boddeke EHWGM, Bogers WM, Bontrop R, Bulthuis R, Bousema T, Clevers H, Coenen TCJJ, van Dam AM, Deen PMT, van Dijk KW, Eggen BJL, Elgersma Y, Erdogan I, Englitz B, Fentener van Vlissingen JM, la Fleur S, Fouchier R, Fitzsimons CP, Frieling W, Haagmans B, Heesters BA, Henckens MJAG, Herfst S, Hol E, van den Hove D, de Jonge MI, Jonkers J, Joosten LAB, Kalsbeek A, Kamermans M, Kampinga HH, Kas MJ, Keijer J, Kersten S, Kiliaan AJ, Kooij TWA, Kooijman S, Koopman WJH, Korosi A, Krugers HJ, Kuiken T, Kushner SA, Langermans JAM, Lesscher HMB, Lucassen PJ, Lutgens E, Netea MG, Noldus LPJJ, van der Meer JWM, Meye FJ, Mul JD, van Oers K, Olivier JDA, Pasterkamp RJ, Philippens IHCHM, Prickaerts J, Pollux BJA, Rensen PCN, van Rheenen J, van Rij RP, Ritsma L, Rockx BHG, Roozendaal B, van Schothorst EM, Stittelaar K, Stockhofe N, Swaab DF, de Swart RL, Vanderschuren LJMJ, de Vries TJ, de Vrij F, van Wezel R, Wierenga CJ, Wiesmann M, Willuhn I, de Zeeuw CI, Homberg JR
Current biology : CB (2020) | 57 citations

Characterization of human FDCs reveals regulation of T cells and antigen presentation to B cells.

Heesters BA^*, van Megesen K, Tomris I, de Vries RP, Magri G, Spits H
The Journal of experimental medicine (2021) | 52 citations

Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens.

Fergusson JR, Morgan MD, Bruchard M, Huitema L, Heesters BA, van Unen V, van Hamburg JP, van der Wel NN, Picavet D, Koning F, Tas SW, Anderson MS, Marioni JC, Holländer GA, Spits H
Frontiers in immunology (2019) | 49 citations

A Meta-Analysis of the Effect of Corticosteroid Injection for Enthesopathy of the Extensor Carpi Radialis Brevis Origin.

Claessen FMAP, Heesters BA, Chan JJ, Kachooei AR, Ring D
The Journal of hand surgery (2016) | 42 citations

Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice.

Küçükköse E, Heesters BA, Villaudy J, Verheem A, Cercel M, van Hal S, Boj SF, Borel Rinkes IHM, Punt CJA, Roodhart JML, Laoukili J, Koopman M, Spits H, Kranenburg O
Journal for immunotherapy of cancer (2022) | 40 citations

Identification of human cytotoxic ILC3s.

Krabbendam L, Heesters BA, Kradolfer CMA, Spits H, Bernink JH
European journal of immunology (2021) | 34 citations

CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn's disease.

Krabbendam L, Heesters BA, Kradolfer CMA, Haverkate NJE, Becker MAJ, Buskens CJ, Bemelman WA, Bernink JH, Spits H
Nature communications (2021) | 32 citations

Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα.

Mooster JL, Le Bras S, Massaad MJ, Jabara H, Yoon J, Galand C, Heesters BA, Burton OT, Mattoo H, Manis J, Geha RS
The Journal of experimental medicine (2015) | 32 citations

L-Rhamnose-containing supramolecular nanofibrils as potential immunosuppressive materials.

Zhao F, Heesters BA, Chiu IM, Gao Y, Shi J, Zhou N, Carroll MC, Xu B
Organic & biomolecular chemistry (2014) | 29 citations

SARS-CoV-2 Spike N-Terminal Domain Engages 9-O-Acetylated α2-8-Linked Sialic Acids.

Tomris I, Unione L, Nguyen L, Zaree P, Bouwman KM, Liu L, Li Z, Fok JA, Ríos Carrasco M, van der Woude R, Kimpel ALM, Linthorst MW, Kilavuzoglu SE, Verpalen ECJM, Caniels TG, Sanders RW, Heesters BA, Pieters RJ, Jiménez-Barbero J, Klassen JS, Boons GJ, de Vries RP
ACS chemical biology (2023) | 23 citations

The Role of Dendritic Cells in S. pneumoniae Transport to Follicular Dendritic Cells.

Heesters BA^*, Carroll MC
Cell reports (2016) | 16 citations

Do follicular dendritic cells regulate lupus-specific B cells?

Heesters BA, Das A, Chatterjee P, Carroll MC
Molecular immunology (2014) | 16 citations

Follicular Dendritic Cell Isolation and Loading of Immune Complexes.

Heesters BA, Van der Poel CE, Carroll MC
Methods in molecular biology (Clifton, N.J.) (2017) | 12 citations

Contextual analysis of immunological response through whole-organ fluorescent imaging.

Woodruff MC, Herndon CN, Heesters BA, Carroll MC
Lymphatic research and biology (2013) | 9 citations

Human CD127 negative ILC2s show immunological memory.

Mathä L, Krabbendam L, Martinez Høyer S, Heesters BA, Golebski K, Kradolfer C, Ghaedi M, Ma J, Stadhouders R, Bachert C, Cardell LO, Zhang N, Holtappels G, Reitsma S, Helgers LC, Geijtenbeek TBH, Coquet JM, Takei F, Spits H, Martinez-Gonzalez I
The Journal of experimental medicine (2024) | 8 citations

The follicular dendritic cell: At the germinal center of autoimmunity?

Krimpenfort LT, Degn SE, Heesters BA^*
Cell reports (2024) | 4 citations

Uniting education, research, healthcare, and society to advance women's heart health.

Schakelaar MY, Maas A, van Ommen ALN, Spiering AE, de Jonge R, Wijchers P, van Rossum G, Heesters BA, de Jong OG, Zandveld J, Rebel HG, Meeldijk J, Pijnappel EW, van Dijk S, Di Maggio A, Nijssen O, Sanders JGF, Hoogerwerf L, van Spaandonk M, Crnko S, Koorman T, Jenniskens K, Onland-Moret NC, van Geelen SM, Ten Broeke T, van Royen-Kerkhof A, Dilaver G, Oliveira S, Kok RJ, van Laake LW, van der Harst P, Spiering W, Rutten FH, van Brussel M, den Ruijter HM, Bovenschen N
The Journal of experimental medicine (2024) | 1 citations

Bacteria activate sensory neurons that modulate pain and inflammation.

Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck Wardenburg J, Hwang SW, Carroll MC, Woolf CJ
Nature (2013) | 80.7 citations per year (944 total)

Induction of IL-10-producing type 2 innate lymphoid cells by allergen immunotherapy is associated with clinical response.

Golebski K, Layhadi JA, Sahiner U, Steveling-Klein EH, Lenormand MM, Li RCY, Bal SM, Heesters BA, Vilà-Nadal G, Hunewald O, Montamat G, He FQ, Ollert M, Fedina O, Lao-Araya M, Vijverberg SJH, Maitland-van der Zee AH, van Drunen CM, Fokkens WJ, Durham SR, Spits H, Shamji MH
Immunity (2021) | 53.5 citations per year (228 total)

Follicular dendritic cells: dynamic antigen libraries.

Heesters BA, Myers RC, Carroll MC
Nature reviews. Immunology (2014) | 48.6 citations per year (529 total)

Endocytosis and recycling of immune complexes by follicular dendritic cells enhances B cell antigen binding and activation.

Heesters BA, Chatterjee P, Kim YA, Gonzalez SF, Kuligowski MP, Kirchhausen T, Carroll MC
Immunity (2013) | 27.5 citations per year (327 total)

Antigen Presentation to B Cells.

Heesters BA, van der Poel CE, Das A, Carroll MC
Trends in immunology (2016) | 24.4 citations per year (206 total)

IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation.

Golebski K, Ros XR, Nagasawa M, van Tol S, Heesters BA, Aglmous H, Kradolfer CMA, Shikhagaie MM, Seys S, Hellings PW, van Drunen CM, Fokkens WJ, Spits H, Bal SM
Nature communications (2019) | 22.8 citations per year (137 total)

Steroid-resistant human inflammatory ILC2s are marked by CD45RO and elevated in type 2 respiratory diseases.

van der Ploeg EK, Golebski K, van Nimwegen M, Fergusson JR, Heesters BA, Martinez-Gonzalez I, Kradolfer CMA, van Tol S, Scicluna BP, de Bruijn MJW, de Boer GM, Tramper-Stranders GA, Braunstahl GJ, van IJcken WFJ, Nagtegaal AP, van Drunen CM, Fokkens WJ, Huylebroeck D, Spits H, Hendriks RW, Stadhouders R, Bal SM
Science immunology (2021) | 22.6 citations per year (97 total)

KLRG1 and NKp46 discriminate subpopulations of human CD117(+)CRTH2(-) ILCs biased toward ILC2 or ILC3.

Nagasawa M, Heesters BA, Kradolfer CMA, Krabbendam L, Martinez-Gonzalez I, de Bruijn MJW, Golebski K, Hendriks RW, Stadhouders R, Spits H, Bal SM
The Journal of experimental medicine (2019) | 22.3 citations per year (129 total)

Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice.

Küçükköse E, Heesters BA, Villaudy J, Verheem A, Cercel M, van Hal S, Boj SF, Borel Rinkes IHM, Punt CJA, Roodhart JML, Laoukili J, Koopman M, Spits H, Kranenburg O
Journal for immunotherapy of cancer (2022) | 16.3 citations per year (40 total)

Trafficking of B cell antigen in lymph nodes.

Gonzalez SF, Degn SE, Pitcher LA, Woodruff MC, Heesters BA, Carroll MC
Annual review of immunology (2011) | 15.4 citations per year (222 total)

Characterization of human FDCs reveals regulation of T cells and antigen presentation to B cells.

Heesters BA^*, van Megesen K, Tomris I, de Vries RP, Magri G, Spits H
The Journal of experimental medicine (2021) | 14.4 citations per year (52 total)

How the COVID-19 pandemic highlights the necessity of animal research.

Genzel L, Adan R, Berns A, van den Beucken JJJP, Blokland A, Boddeke EHWGM, Bogers WM, Bontrop R, Bulthuis R, Bousema T, Clevers H, Coenen TCJJ, van Dam AM, Deen PMT, van Dijk KW, Eggen BJL, Elgersma Y, Erdogan I, Englitz B, Fentener van Vlissingen JM, la Fleur S, Fouchier R, Fitzsimons CP, Frieling W, Haagmans B, Heesters BA, Henckens MJAG, Herfst S, Hol E, van den Hove D, de Jonge MI, Jonkers J, Joosten LAB, Kalsbeek A, Kamermans M, Kampinga HH, Kas MJ, Keijer J, Kersten S, Kiliaan AJ, Kooij TWA, Kooijman S, Koopman WJH, Korosi A, Krugers HJ, Kuiken T, Kushner SA, Langermans JAM, Lesscher HMB, Lucassen PJ, Lutgens E, Netea MG, Noldus LPJJ, van der Meer JWM, Meye FJ, Mul JD, van Oers K, Olivier JDA, Pasterkamp RJ, Philippens IHCHM, Prickaerts J, Pollux BJA, Rensen PCN, van Rheenen J, van Rij RP, Ritsma L, Rockx BHG, Roozendaal B, van Schothorst EM, Stittelaar K, Stockhofe N, Swaab DF, de Swart RL, Vanderschuren LJMJ, de Vries TJ, de Vrij F, van Wezel R, Wierenga CJ, Wiesmann M, Willuhn I, de Zeeuw CI, Homberg JR
Current biology : CB (2020) | 12.6 citations per year (57 total)

Follicular Dendritic Cell Activation by TLR Ligands Promotes Autoreactive B Cell Responses.

Das A, Heesters BA, Bialas A, O'Flynn J, Rifkin IR, Ochando J, Mittereder N, Carlesso G, Herbst R, Carroll MC
Immunity (2017) | 12.5 citations per year (104 total)

Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes.

Heesters BA^*, Lindqvist M, Vagefi PA, Scully EP, Schildberg FA, Altfeld M, Walker BD, Kaufmann DE, Carroll MC
PLoS pathogens (2015) | 12.3 citations per year (116 total)

SARS-CoV-2 Spike N-Terminal Domain Engages 9-O-Acetylated α2-8-Linked Sialic Acids.

Tomris I, Unione L, Nguyen L, Zaree P, Bouwman KM, Liu L, Li Z, Fok JA, Ríos Carrasco M, van der Woude R, Kimpel ALM, Linthorst MW, Kilavuzoglu SE, Verpalen ECJM, Caniels TG, Sanders RW, Heesters BA, Pieters RJ, Jiménez-Barbero J, Klassen JS, Boons GJ, de Vries RP
ACS chemical biology (2023) | 11.5 citations per year (23 total)

Human CD127 negative ILC2s show immunological memory.

Mathä L, Krabbendam L, Martinez Høyer S, Heesters BA, Golebski K, Kradolfer C, Ghaedi M, Ma J, Stadhouders R, Bachert C, Cardell LO, Zhang N, Holtappels G, Reitsma S, Helgers LC, Geijtenbeek TBH, Coquet JM, Takei F, Spits H, Martinez-Gonzalez I
The Journal of experimental medicine (2024) | 10.3 citations per year (8 total)

Loss of intestinal sympathetic innervation elicits an innate immune driven colitis.

Willemze RA, Welting O, van Hamersveld P, Verseijden C, Nijhuis LE, Hilbers FW, Meijer SL, Heesters BA, Folgering JHA, Darwinkel H, Blancou P, Vervoordeldonk MJ, Seppen J, Heinsbroek SEM, de Jonge WJ
Molecular medicine (Cambridge, Mass.) (2019) | 9.3 citations per year (59 total)

CD127+ CD94+ innate lymphoid cells expressing granulysin and perforin are expanded in patients with Crohn's disease.

Krabbendam L, Heesters BA, Kradolfer CMA, Haverkate NJE, Becker MAJ, Buskens CJ, Bemelman WA, Bernink JH, Spits H
Nature communications (2021) | 8.9 citations per year (32 total)

Trans-nodal migration of resident dendritic cells into medullary interfollicular regions initiates immunity to influenza vaccine.

Woodruff MC, Heesters BA, Herndon CN, Groom JR, Thomas PG, Luster AD, Turley SJ, Carroll MC
The Journal of experimental medicine (2014) | 8.4 citations per year (91 total)

Identification of human cytotoxic ILC3s.

Krabbendam L, Heesters BA, Kradolfer CMA, Spits H, Bernink JH
European journal of immunology (2021) | 8.2 citations per year (34 total)

Complexity and Diversity of the Mammalian Sialome Revealed by Nidovirus Virolectins.

Langereis MA, Bakkers MJ, Deng L, Padler-Karavani V, Vervoort SJ, Hulswit RJ, van Vliet AL, Gerwig GJ, de Poot SA, Boot W, van Ederen AM, Heesters BA, van der Loos CM, van Kuppeveld FJ, Yu H, Huizinga EG, Chen X, Varki A, Kamerling JP, de Groot RJ
Cell reports (2015) | 7.8 citations per year (77 total)

Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens.

Fergusson JR, Morgan MD, Bruchard M, Huitema L, Heesters BA, van Unen V, van Hamburg JP, van der Wel NN, Picavet D, Koning F, Tas SW, Anderson MS, Marioni JC, Holländer GA, Spits H
Frontiers in immunology (2019) | 7.7 citations per year (49 total)

A Meta-Analysis of the Effect of Corticosteroid Injection for Enthesopathy of the Extensor Carpi Radialis Brevis Origin.

Claessen FMAP, Heesters BA, Chan JJ, Kachooei AR, Ring D
The Journal of hand surgery (2016) | 4.9 citations per year (42 total)

The murine coronavirus hemagglutinin-esterase receptor-binding site: a major shift in ligand specificity through modest changes in architecture.

Langereis MA, Zeng Q, Heesters BA, Huizinga EG, de Groot RJ
PLoS pathogens (2012) | 4.7 citations per year (63 total)

The follicular dendritic cell: At the germinal center of autoimmunity?

Krimpenfort LT, Degn SE, Heesters BA^*
Cell reports (2024) | 3.5 citations per year (4 total)

Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα.

Mooster JL, Le Bras S, Massaad MJ, Jabara H, Yoon J, Galand C, Heesters BA, Burton OT, Mattoo H, Manis J, Geha RS
The Journal of experimental medicine (2015) | 3.1 citations per year (32 total)

L-Rhamnose-containing supramolecular nanofibrils as potential immunosuppressive materials.

Zhao F, Heesters BA, Chiu IM, Gao Y, Shi J, Zhou N, Carroll MC, Xu B
Organic & biomolecular chemistry (2014) | 2.7 citations per year (29 total)

Uniting education, research, healthcare, and society to advance women's heart health.

Schakelaar MY, Maas A, van Ommen ALN, Spiering AE, de Jonge R, Wijchers P, van Rossum G, Heesters BA, de Jong OG, Zandveld J, Rebel HG, Meeldijk J, Pijnappel EW, van Dijk S, Di Maggio A, Nijssen O, Sanders JGF, Hoogerwerf L, van Spaandonk M, Crnko S, Koorman T, Jenniskens K, Onland-Moret NC, van Geelen SM, Ten Broeke T, van Royen-Kerkhof A, Dilaver G, Oliveira S, Kok RJ, van Laake LW, van der Harst P, Spiering W, Rutten FH, van Brussel M, den Ruijter HM, Bovenschen N
The Journal of experimental medicine (2024) | 1.9 citations per year (1 total)

The Role of Dendritic Cells in S. pneumoniae Transport to Follicular Dendritic Cells.

Heesters BA^*, Carroll MC
Cell reports (2016) | 1.8 citations per year (16 total)

Do follicular dendritic cells regulate lupus-specific B cells?

Heesters BA, Das A, Chatterjee P, Carroll MC
Molecular immunology (2014) | 1.5 citations per year (16 total)

Follicular Dendritic Cell Isolation and Loading of Immune Complexes.

Heesters BA, Van der Poel CE, Carroll MC
Methods in molecular biology (Clifton, N.J.) (2017) | 1.4 citations per year (12 total)

Contextual analysis of immunological response through whole-organ fluorescent imaging.

Woodruff MC, Herndon CN, Heesters BA, Carroll MC
Lymphatic research and biology (2013) | 0.8 citations per year (9 total)